bird icon for twitter bird icon for twitter


Depressed? Here's why you can't get the medicines that you need

how the FDA's drug approval process is based on big-money politics and the drug war ideology of substance demonization

by Brian Ballard Quass, the Drug War Philosopher

December 21, 2022



An open letter to Roland Griffiths, Professor in the Neuropsychopharmacology of Consciousness at Johns Hopkins School of Medicine


Dear Professor Griffiths:

As a 64-year-old depressive who could benefit from MDMA use, I am frustrated by the FDA's hypocritical and unscientific standard for approving psychoactive drugs. They seem to think that one study that cites potential long-term negative effects can block approval, as if the only stakeholders in the approval game were juvenile delinquents who might misuse the drug.

April 2025 Update

What about the millions of Americans living lives of what Thoreau called "quiet despair"? What about the thousands of American soldiers who have gone for the last four decades without a godsend therapy for PTSD? What about the thousands of kids in South America who have lost parents to our Drug War or the kids killed in our inner cities due to the violence that Prohibition creates out of whole cloth? Why are the only stakeholders considered to be white American sons and daughters who have to be saved from their own ignorance, an ignorance that we support by teaching them to fear psychoactive substances rather than to understand them?

In fact, the use of MDMA has been MORE than safe, historically speaking; it has been BENEFICIAL too. Yes, beneficial. It has resulted in a literally unprecedented world in which everybody got along. As one British rave-scene DJ said: "It was black and white, Asian, Chinese, all up in one building." But, of course, that's of no concern to the FDA. They never consider the "up" sides of psychoactive drugs because Drug War ideology tells them that there can be no "up" sides to "drug use." The Drug War is far more important than mere peace, love and understanding, apparently. Meanwhile, questions like these are never asked in the FDA drug approval process: "How many suicides might the use of this drug prevent? How many cases of road rage? How many school shootings? How many users might cut back on cigarettes and alcohol, or else never start using them in the first place?"

Okay, let's grant that the long-term and excessive use of MDMA may be problematic, though folks like Rick Doblin and Charles Wininger disagree: why not publicize that fact rather than using it as an excuse to block use by anyone, ever, at any time, for any reason? But let's not be hypocritical. If overuse of alcohol and anti-depressants results in downsides, then let's be sure to trumpet those as well, if only to keep young people from cynically rejecting all government warnings based on the FDA's obvious hypocrisy in singling out MDMA for such criticism.

This go-slow approach to drug approval (more accurately called a "go-glacial approach") has now kept me from accessing plant medicine for my entire life. Moreover, it is glaringly political in nature. Although it has been used safely for generations now, MDMA is criminalized based on a mere thread of potentially negative evidence; meanwhile 1 in 4 American women are chemically dependent upon Big Pharma meds for life, most of which were never intended for long-term use, and the FDA has no problem with that whatsoever. In fact, thousands of these "patients for life" are screaming bloody murder on the Internet about the downsides of SSRI withdrawal, which are far from theoretical in nature: brain zaps, dizziness, foggy thinking, etc. And yet anti-depressants remain the go-to drug for depression and other mood disorders, and those who fail to respond to them, we're told, just have to find the right brand name. In other words, the drugs themselves are supposedly beyond reproach. The problems, if any arise, are blamed on the user's finicky response to them.

The whole system reeks of politicization, big money, and double standards.

And now scientists like Dr. Robert Glatter are holding laughing gas to the same absurd standard, a standard that is never applied to Big Pharma drugs.

>Anti-depressants weren't meant to be taken for life. Only when Big Pharma learned they were addictive did psychiatrists tell us to stay on our meds FOREVER.

Instead of telling the millions of depressed how to use laughing gas safely, the FDA assumes that the only stakeholders in the approval process are juvenile delinquents who cannot be educated, and so they slam on the brakes of legalization, ignoring the many invisible stakeholders who must pay the price for their purblind analysis: folks like myself, who have spent their entire life without godsend psychoactive medicines, all because the FDA has a hypocritical and money-driven approach to approving drugs. And so laughing gas, a drug whose use inspired the ontology of William James, is placed off-limits, not just for the depressed but for the philosopher and truth seeker as well.

Thank you for your time. As you continue your work with drugs like MDMA, I urge you to speak up on behalf of folks like myself, one of the millions of forgotten stakeholders in America's corrupt and biased drug-approval process. For I fear that many who watch your interviews get the impression that the FDA is moving slowly but wisely toward legalizing drugs like MDMA -- whereas the FDA's drug-approval decisions are clearly based on politics and a variety of false assumptions inspired by the drug-war ideology of substance demonization.

Related tweet: January 13, 2023

The use of laughing gas changed William James' ideas about the very nature of reality. To outlaw such substances is to outlaw human advancement.




Author's Follow-up:

April 21, 2025

picture of clock metaphorically suggesting a follow-up




In a sane world, scientists would not be placed in charge of deciding whether psychoactive medicines can be helpful for living, breathing human beings. It is a category error to place them in such role. It is precisely like placing Dr. Spock of Star Trek in charge of emotional health. He would start by ignoring everything that is glaringly obvious. Besides, even if drugs have risks, that tells us nothing in itself. The question is whether the risks are worth it given the user's goals in life. That is not a question for neuroscience -- it is a question concerning what one values in life. The risk of drug use must never be considered in the abstract as we do today, but against the goals, the hopes and dreams, of the user. Avicenna, who was a big fan of opium, is said to have valued a wide life over a long one. Sherlock Holmes clearly valued a life of intense mental focus. Are materialists scientists experts on deciding the value of a "wide life" or of mental focus? Of course not.

Antidepressants




WARNING: Don't bother trying to get off antidepressants unless you are truly committed to the idea in the name of healthcare liberty. You have to be committed to such a goal heart and soul, merely to have a chance at success. For long-term users, it can be a real challenge. It is interesting how psychiatrists flip the script on this subject, by the way: they claim that the hideous withdrawal symptoms somehow prove that the user needed the drug all along. But this is obvious nonsense. This can be seen in the fact that these same psychiatrists would never say such a thing about heroin users: that their angst upon quitting the drug is a sign that the drug was actually working for them.

Note that I am not saying that antidepressants are drugs from hell -- but rather that they BECOME drugs from hell thanks to drug prohibition. Drug prohibition outlaws all drugs that could help you get off of antidepressants and so live a fulfilled life without becoming a ward of the healthcare state. We need merely to re-legalize Mother Nature's medicines. Why do we fail to do so? Because we judge drugs based on the following silly and inhumane algorithm: namely, that a substance that can be misused, even in theory, by a white American young person at one dose when used for one reason in one circumstance must not be used by anybody at any dose in any circumstances...

Suppose you lived in the Punjab in 1500 BCE and were told that Soma was illegal but that the mental health establishment had medicines which you could take every day of your life for your depression. Would it not be an enormous violation of your liberty to be told that you could not worship Soma and its attendant gods and incarnations? Would it not be an enormous violation of your liberty to be told that you cannot partake of the drink of the Gods themselves, the Soma juice?

Well, guess what? Your liberty is suppressed in that very fashion by modern drug prohibition: you are denied access to all medicines that inspire and elate. Seen in this light, antidepressants are a slap in the face to a freedom-loving people. They are a prohibitionist replacement for a host of obvious treatments, none of which need turn the user into a patient for life, and some of which could even inspire new religions.

The Hindu religion would not exist today had the DEA been active in the Punjab in 1500 BCE.

So do antidepressants make sense?

This question has two very different answers, depending on whether you recognize that prohibition exists or not. Of course, most Americans pretend that Drug War prohibition does not exist, or at least that it has no effect on their lives -- and so they happily become Big Pharma patients for life. They flatter themselves that they are thereby treating their problems "scientifically." What they fail to realize, of course, is that it is a category error for materialist scientists to treat mind and mood conditions in the first place.

Why? Because scientists are behaviorists when it comes to drugs, which means that they ignore all obvious positive effects of drugs: all anecdote, all history and all psychological common sense -- and instead try to cure you biochemically. And what has been the result of this purblind approach to mind and moods, this search for the Holy Grail of materialist cures for depression? The result has been the greatest mass pharmacological dystopia of all time, thanks to which 1 in 4 American women are dependent on Big Pharma pills for life.



  • America's Great Anti-Depressant Scam
  • And don't get me started on antidepressants!
  • Brahms is NOT the best antidepressant
  • Depressed? Here's why you can't get the medicines that you need
  • Depressed? Here's why.
  • Depression is real, says the APA, and they should know: they cause it!
  • Getting off antidepressants in the age of the Drug War
  • How the Drug War Screws the Depressed
  • How the Drug War Tramples on the Rights of the Depressed
  • How to end the war in Mexico, stop inner-city killings and cure depression in one easy step
  • I'll See Your Antidepressants and Raise You One Huachuma Cactus
  • Psychiatrists Tell Me That It's Wrong to Criticize Antidepressants
  • Replacing antidepressants with entheogens
  • Surviving the Surviving Antidepressants website
  • The common sense way to get off of antidepressants
  • The Crucial Connection Between Antidepressants and the War on Drugs
  • The Depressing Truth About SSRIs
  • The Philosophical Significance of the Use of Antidepressants in the Age of Drug Prohibition
  • The real reason for depression in America
  • Using Opium to Fight Depression
  • Using plants and fungi to get off of antidepressants
  • What Malcolm X got right about drugs
  • Why doctors should prescribe opium for depression
  • Why SSRIs are Crap





  • Ten Tweets

    against the hateful war on US




    The best step we could take in harm reduction is re-legalizing everything and starting to teach safe use. Spend the DEA's billions on "go" teams that would descend on locations where drugs are being used stupidly -- not to arrest, but to educate.

    It is a truism to say that we cannot change the world and that therefore we have to change ourselves -- but the drug war outlaws even this latter option.

    "The Legislature deliberately determines to distrust the very people who are legally responsible for the physical well-being of the nation, and puts them under the thumb of the police, as if they were potential criminals." -- Aleister Crowley on drug laws

    The "scheduling" system is completely anti-scientific and anti-patient. It tells us we can make a one-size-fits-all decision about psychoactive substances without regard for dosage, context of use, reason for use, etc. That's superstitious tyranny.

    "Drugs" is imperialist terminology. In the smug self-righteousness of those who use it, I hear Columbus's disdain for the shroom use of the Taino people and the Spanish disdain for the coca use of the Peruvian Indians.

    The Drug War is a crime against humanity.

    The DEA is a Schedule I agency. It has no known positive uses and is known to cause death and destruction.

    Drug-designing chemists have no expertise in deciding what constitutes a cure for depression. As Schopenhauer wrote: "The mere study of chemistry qualifies a man to become an apothecary, but not a philosopher."

    Scientists are not the experts on psychoactive medicines. The experts are painters and artists and spiritualists -- and anyone else who simply wants to be all they can be in life. Scientists understand nothing of such goals and aspirations.

    Folks like Sabet accuse folks like myself of ignoring the "facts." No, it is Sabet who is ignoring the facts -- facts about dangerous horses and free climbing. He's also ignoring all the downsides of prohibition, whose laws lead to the election of tyrants.


    Click here to see All Tweets against the hateful War on Us






    News Flash: Drug Use Can Be a Good Thing!
    The Michael Pollan Fallacy


    Copyright 2025 abolishthedea.com, Brian Quass

    (up)