
During our stifling walk through Taboga Island on a typical summer day in Panama in February 2026, our resident tour guide brought us to the oceanside house of Francisco Pizarro, where the Conquistador lived the good life with the help of his encomienda of 150 indigenous slaves before setting off to conquer Peru, not once, but twice. I was startled to learn that a house with such a name even existed on the so-called "Island of Flowers," let alone that it was located on a street that unapologetically boasted the same controversial name. My astonishment only grew when our guide informed our small group of day trippers that the house is still in the hands of Pizarro's descendants to this very day. "What?", I thought to myself. "Did not the indigenous people of Peru successfully demand the removal of the equestrian statue of Pizarro from the Lima capital in 2003? Why is this house and street tolerated by the Mestizo population of the island, given their tangible connections with the peoples whom the Spaniard decimated for nepotistic gain, the encomiendas thus generated being shared with his three equally ruthless brothers?"

William James knew that there were substances that could elate. However, it never occurred to him that we should use such substances to prevent suicide. It seems James was blinded to this possibility by his puritanical assumptions.
My impression has been that the use of cocaine over a long time can bring about lasting improvement..." --Sigmund Freud, On Cocaine, 1884
The evidence has been in for well over a century now: people want to use psychoactive substances to transcend the rational mind. It's about time we stopped punishing them for that.
To oppose the Drug War philosophically, one has to highlight its connections to both materialism and the psychiatric pill mill. And that's a problem, because almost everyone is either a Drug Warrior or a materialist these days and has a vested interest in the continuation of the psychiatric pill mill.
Scientists hold holistically working drugs to reductionist standards, thereby practicing a sort of pharmacological colonialsm.
Suicidal people should be given drugs that cheer them up immediately and whose use they can look forward to. The truth is, we would rather such people die than to give them such drugs, that's just how bamboozled we are by the war against drugs.
In the board game "Sky Team," you collect "coffees" to improve your flying skills. Funny how the use of any other brain-focusing "drug" in real life is considered to be an obvious sign of impairment.
Ann Lemke's case studies make the usual assumptions: getting free from addiction is a morality tale. No reference to how the drug war promotes addiction and how banned drugs could solve such problems. She does not say why daily SSRI use is acceptable while daily opium use is not. Etc.
In 1886, coca enthusiast JJ Tschudi referred to prohibitionists as 'kickers.' He wrote: "If we were to listen to these kickers, most of us would die of hunger, for the reason that nearly everything we eat or drink has fallen under their ban."
It's a category error to say that scientists can tell us if psychoactive drugs "really work." It's like asking Dr. Spock of Star Trek if hugging "really works." ("Hugging is highly illogical, Captain.")

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