Speaking Truth to Big Pharma
an open letter to the Heffter Research Institute
by Brian Ballard Quass, the Drug War Philosopher
December 25, 2019
In the book Psychedelic Medicine, Dr. Richard Louis Miller refers to a lack of support for psychedelic medicines, especially LSD, concluding that there are only a handful of specialists who are pursuing the work and that the public, especially in Britain, are largely indifferent to the whole topic.
In my opinion, this indifference exists only because no one has yet attempted to connect the dots between the outlawing of psychedelic therapy and the current sad state of depression therapy in America, namely that addictive and starkly inadequate solution of Big Pharma known as SSRIs and SNRIs. If this connection were understood by the depressed public, I imagine they would be plenty motivated to support change.
The dots may be connected as follows:
Psychedelic therapy showed great promise for the depressed and it's non-addictive.
The government banned that therapy half a century ago.
As a result, the depressed have been shunted off onto addictive medicines that simply do not work as claimed, drugs that actually create the chemical imbalance that they purport to fix. These ineffective medicines are expensive, must be taken daily and turn the pill-taker into an eternal patient, since they have to visit a psychiatrist every 3 months of their life in order to be catechized about their mental health. This is the exact opposite of an empowering therapy. Speaking personally, I consider it highly demoralizing (a fact that I've never heard psychiatrists recognize, let alone regret).
I personally have been a guinea pig for Big Pharma for the last 50 years, and their nostrums have not worked. Worse yet, they have conduced to anhedonia, a kind of emotional flat-lining - making life bearable, perhaps, but only by removing highs and lows. What's more, my particular "medicine," Effexor 1 , is so addictive (productive of chemical dependence, if you prefer) that my own shrink tells me not to bother trying to get off it! He says that an NIH study shows a 95% recidivism rate 2 for those who try.
I am plenty upset about this. That's why I'm dumbfounded and frustrated to read Miller's no-doubt-correct observation that there is little public interest in changing the status quo. Don't the depressed millions see what's going on? Apparently not. Not yet anyway. And this must change if organizations such as Heffter want to be in the mainstream and reap monetary donations accordingly.
The current tendency of psychedelic advocates (Like Lauren Slater in Blue Dreams) is to write as if psychedelics are just another way to approach the problem of depression and are in no way meant to take the place of Big Pharma 's addictive meds. (Slater is so "soft" on psychiatry's failings that she even supports shock therapy - a vicious therapy that only becomes a default option thanks to America's anti-scientific outlawing of psychoactive plants.)
This failure to "take on" Big Pharma also results in the psychedelic movement "reckoning without its host," at least when it comes to depression therapy. Thus we see that many otherwise exciting clinical trials are completely off-limits to those taking SSRIs and SNRIs. This means that the victims of the Drug War—the vast majority of the depressed—are not even eligible for the cures being brought forward by the psychedelic movement. And yet this same movement wrings its hands about a lack of funding?
How can one expect funding from a demographic for whom one's research is essentially useless? More than 1 in 8 Americans are addicted to SSRIs and SNRIs (1 in 4 women, according to psychiatrist Julie Holland). They are the folks you need to reach, not the lucky few who so far have had little or no contact with such disempowering poisons.
If the psychedelic movement really wants to excite the depressed layperson, they will work to develop a therapy that simultaneously eases depression while weaning a patient off of their SSRI. This would involve, in broad strokes, a ratcheting up of psychedelic doses for the patient as SSRI intake is decreased in proportion. Your researchers already have one guinea pig for use in trialing such a therapy: namely myself.
Creating a successful movement for psychedelic therapy requires creating a movement for the overthrow of the addictive Big Pharma status quo. Until professionals, authors and organizations realize this and change their rhetoric accordingly, a truly motivated fan club of psychedelic therapy will remain limited to the handful of forward-thinking individuals who were cited by Miller in "Psychedelic Medicine."
PS This is essentially the reason why I started my website, AbolishTheDEA.com, to connect the dots between the Drug War and the depression crisis in America. Part of that task is to point out the inconvenient truth that Big Pharma 3 4 's cures - made necessary only thanks to the existence of that Drug War -- are expensive, addictive - and bad for morale, since they turn the depressed into eternal patients.
Notes:
1: How Drug Prohibition makes it impossible to get off of Effexor and other Big Pharma drugs DWP (up)
2: I have been unable to confirm this stat. But the WHO notes clinical recidivism rates for depression ranging from 50% to 85%. Do we count that as a recidivism rate of Effexor? Not when Biopharma is paying 75% of The FDA’s Drug Division Budget, as reported by John LaMattina in the Sep 22, 2022 edition of Forbes magazine. (up)
3: Seife, Charles. 2012. “Is Drug Research Trustworthy?” Scientific American 307 (6): 56–63. https://doi.org/10.1038/scientificamerican1212-56. (up)
4: LaMattina, John. n.d. “Why Is Biopharma Paying 75% of the FDA’s Drug Division Budget?” Forbes. https://www.forbes.com/sites/johnlamattina/2022/09/22/why-is-biopharma-paying-75-of-the-fdas-drug-division-budget/. (up)
Ten Tweets
against the hateful war on US
People talk about how dangerous Jamaica is -- but no one reminds us that it is all due to America's Drug War. Yes, cannabis and psilocybin are legal there, but plenty of drugs are not, and even if they were, their illegality elsewhere would lead to fierce dealer rivalry.
News flash: certain mushrooms can help you improve your life! It's the biggest story in the history of mycology! And yet you wouldn't know it from visiting the websites of most mushroom clubs.
The Holy Trinity of the Drug War religion is Janis Joplin, Jimi Hendrix, and John Belushi. "They died so that you might fear psychoactive substances with all your heart and with all your soul and with all your mind and with all your strength."
When people tell us there's nothing to be gained from using mind-improving drugs, they are embarrassing themselves. Users benefit from such drugs precisely to the extent that they are educated and open-minded. Loudmouth abstainers are telling us that they lack these traits.
The DEA has done everything it can to keep Americans clueless about opium and poppies. The agency is a disgrace to a country that claims to value knowledge and freedom of information.
Q: Where can you find almost-verbatim copies of the descriptions of religious experiences described by William James? A: In descriptions of user reports of "trips" on drugs ranging from coca to opium, from MDMA to laughing gas.
Drug prohibition is the biggest tyranny imaginable. It is the government control of pain relief. It is government telling us how and how much we are allowed to think and feel in this life.
Immanuel Kant wrote that scientists are scornful about metaphysics yet they rely on it themselves without realizing it. This is a case in point, for the idea that euphoria and visions are unhelpful in life is a metaphysical viewpoint, not a scientific one.
Ann Lemke's case studies make the usual assumptions: getting free from addiction is a morality tale. No reference to how the drug war promotes addiction and how banned drugs could solve such problems. She does not say why daily SSRI use is acceptable while daily opium use is not. Etc.
This is the "Oprah fallacy," which has led to so much suffering. She told women they were fools if they accepted a drink from a man. That's crazy. If we are terrified by such a statistically improbable event, we should be absolutely horrified by horses and skateboards.
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Copyright 2025, Brian Ballard Quass
Contact: quass@quass.com
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